Peptides are biological molecules consisting of short chains of amino acid monomers linked together by peptide (amide) bonds. They are found in the structure of all living organisms and play a vital role in various biological activities. A sequence is typically classified as a “peptide” when it contains 2 to 50 amino acids, whereas larger amino acid chains (more than 50 amino acids) are recognized as “proteins.” To date, more than 7,000 types of peptides have been identified. Given their diverse involvement in the body’s chemistry, they can be categorized based on their functional roles.
Today, the use of peptides as novel therapeutics is on the rise, driven by their high potency, low risk of adverse effects, and favorable clinical outcomes. Currently, over 60 peptide-based drugs have been developed and marketed globally by leading pharmaceutical companies. However, the direct clinical application of peptides is often hindered by their chemical instability and rapid loss of efficacy; therefore, specific structural modifications are required for therapeutic use. Peptides are primarily utilized in the treatment of metabolic disorders (such as diabetes and obesity), oncological conditions, neuropsychiatric disorders, supportive care for cancer chemotherapy, and immunomodulation.
Today, the use of peptides as novel therapeutics is on the rise, driven by their high potency, low risk of adverse effects, and favorable clinical outcomes. Currently, over 60 peptide-based drugs have been developed and marketed globally by leading pharmaceutical companies. However, the direct clinical application of peptides is often hindered by their chemical instability and rapid loss of efficacy; therefore, specific structural modifications are required for therapeutic use. Peptides are primarily utilized in the treatment of metabolic disorders (such as diabetes and obesity), oncological conditions, neuropsychiatric disorders, supportive care for cancer chemotherapy, and immunomodulation.
Hazardous and High-Potency drugs refer to substances that, even at extremely low concentrations, can elicit significant effects, including pharmacological impacts, carcinogenicity, teratogenicity, reproductive and fertility disorders, organ toxicity at low doses, and genotoxicity. In general, the high toxicity and the specialized requirements for production, analysis, and storage are the primary constraints in manufacturing these drugs. These processes necessitate specialized equipment, which has limited the number of global manufacturers in this field.
Biosun Pharmed utilizes state-of-the-art manufacturing machinery and Isolator Technology across all production stages. This approach not only ensures product quality but also guarantees the safety and health of personnel and the environment. By leveraging standard classified cleanrooms and implementing fully automated Cleaning-in-Place (CIP) and Sterilization-in-Place (SIP) systems to prevent personnel contact with drug residues, the company has established the capability to produce these products in various dosage forms. These include vials and Pre-filled Syringes (PFS) in both liquid and lyophilized (freeze-dried) formats, in full compliance with cGMP and other contemporary international standards.
